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1 Equivalency study of syringe filters in situ Featured

An unbiased study was conducted by a pharmaceutical company that compared market leading brands of syringe filters in situ to the MicroSolv AQ™ syringe filters. The results were that MicroSolv AQ™…

2 Why your lab should adopt TYPE-C HPLC Technology Featured

These two 4 page papers give many reasons why modern chromatography laboaratories are adopting the Cogent TYPE-C silica based HPLC columns. Saving time, saving money and mostly better science. © Copyright…

3 AQ™ Brand Polypropylene Vial Study (LC-MS) compared to market leading vial.

Many scientists use a very common 300µL plastic (polypropylene) vial for chromatography (HPLC) when they have compounds that stick to glass. With the advancement of LCMS, HILIC and ANP chromatography…

4 AQ™ Brand PP Inserts Study (LC-MS) compared to market leading PP Vials

Many scientists use a very common 300µL plastic (polypropylene) vial for chromatography (HPLC) when they have compounds that stick to glass. With the advancement of LCMS, HILIC and ANP chromatography…

5 Cogent UDA HPLC Column Use & Application

Ion exchange chromatography can be a useful tool available to the analytical chemist. In this separation mode, an ionized moiety on the stationary phase interacts electrostatically with an oppositely…

6 Comparison of AQ™ Brand NDX™ depth filters to Market Leader

The MicroSolv Advanced Quality Depth Syringe Filter NDX™ was tested for extractables, hold up volume and filter lifetime against the market leader. In the first two cases, the NDX™ clearly outperforms…

7 Effect of Diluent on Analyte Adsorption to RSA Glass Vials

It is well known that silanol groups present on the surface of Type I autosampler glass vials contribute to quantitative loss in the case of basic analytes. This is believed to occur primarily by electrostatic…

8 Extractable and Retention Volume Study of MicroSolv AQ Brand NDX-Depth Filters

The MicroSolv AQ Brand NDX-Depth 0.45um nylon Filters were compared to those from a different manufacturer. A solvent of 70:30 acetonitrile:DI water was passed through each filter type. In one instance,…

9 Fast Analysis of Human Normal Immunoglobulin using CElixirPro3

Introduction Human normal immunoglobulin for intravenous administration (IVIg) is a liquid or freeze-dried preparation containing mainly immunoglobulin G (IgG), while albumin may be added as stabilizer…

10 Histamine Application

Histamine is a naturally occurring compound that is metabolized via histidine decarboxylase from the amino acid histidine (see Figure 1 for structure). Although it plays a wide variety of beneficial biochemical…

11 Proteins and Peptides with Capillary Electrophoresis using CElixirPro3

Introduction The CElixirPro3™ kit uses Nitrilotri(trimethyl)phosphonic acid (NTMP) as buffer. NTMP is characterized by 7 pKa’s, allowing the user to design buffers between pH 4 and 7.2. Furthermore…

12 Top 10 reasons to learn more about TYPE-C HPLC columns

This 4 page download gives technical reasons why TYPE-C (silica hydride) HPLC columns are different and the TOP 10 reasons you should learn more about Cogent TYPE-C is provided. © Copyright MicroSolv…

13 Using Acetone in an HPLC Mobile Phase

Under suitable conditions, acetone can act as a useful solvent for an HPLC mobile phase and like acetonitrile, it is a polar aprotic solvent. Acetone can give comparable retention in many cases, thereby…

14 Using Aqueous Normal Phase to your advantage - Download

This article has a r page white paper attached that provides a stron argument for using Aqueous Normal Phase (ANP) HPLC for hydrophilic compounds especially with LCMS. © Copyright MicroSolv Technology…

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